Effects & Benefits
The action mechanisms and different effects of nootropic supplements.
The notion “Nootropic” refers to any drug or compound, which is capable of enhancing cognitive functions without causing any negative consequences to the brain. The functions that are improved by such supplements, usually comprise memory, alertness, studying skills, focusing and reasoning abilities, as well as creativity and motivation.
Further, we shall take a closer look at the effects that the brain boosters may offer you. However, it is impossible to consider the benefits of action without taking a peek into the action mechanism. And based on this aspect, 7 classes have been singled out, and namely:
#1. Stimulants, #2. Racetams, #3. Adaptogens, #4. Cholinergics, #5. Dopaminergics, #6. Metabolics, #7. Serotonergics.
The main effect of this Nootropics type is often associated with such drugs, as highly potent Modafinil, amphetamine Adderall and the natural nootropic caffeine. The effects that you may get from the brain boosters of this class, include enhanced attentiveness, energy level and watchfulness, thus helping you achieve an improvement of your memorizing, processing, focusing, and other thinking processes.
The negative point about the stimulants is the aftereffect they produce. When the stimulant’s action mitigates or totally runs out, you might feel totally worn out. Besides, the risk of adverse events is very high.
Either way, if you are still planning on using the stimulants nootropic class, note that Modafinil, or its OTC alternative Adrafinil are best for use. The action mechanism of Modafinil is quite unique, and enables this drug to enhance alertness and overall mental potential, as well as to lower tiredness and stress.
Modafinil is best to be used occasionally or in cycles. Prolonged use is not advised, though students and people, operating in spheres with high requirements, contribute to the growing popularity of this nootropic.
Racetams make up a nootropics type the action of which resembles the action of Cholinergics class. Though, it does differ from the way it actually produces the beneficial effects. The brain boosters that belong to this category work through improving the acetylcholine receptors susceptibility, thus increasing the efficacy of the neurons communication.
Racetams nootropics differ by the range of the effects produced, though what they mostly do in your brain is increasing the cholinergic activity.
Digging deeper into the information, you will find that some racetams increase the density of receptors in hippocampus, while the others enhance the neurons development. These changes affect such mentally potential zones, like verbal-reasoning aptitude, problem solving ability and memory.
Piracetam is a well-known member of the racetam class, created in the sixties of the 20th century. You may also find several other members of this group, which are based on Piracetam. Another compound, which is at times thought to belong to the same family, is Noopept, but its action mechanism differs and it is also one thousand times more potent than Piracetam.
If you decide to use any drug from this group, you should be aware of the fact that you will have to take plenty of high-quality Choline with it, since the racetams are very likely to promote strong headaches if you don’t. Aside from this unpleasant effect, racetam family is almost non-toxic.
Passion Flower, Ginseng, Gotu Kola, St. Johns Wort, and Kava Kava are the most commonly used adaptogens in today’s market of cognitive enhancers. This class of nootropics aims on improving the balance in brain cells through supporting overall body state.
These nootropics contain natural ingredients and actually do provide several pleasant effects to mental performance and health. Even though Adaptogens are not so well figured, still they manage to lower the susceptibility to the factors of environmental stress, which may negatively affect the systems of your cells.
The effect provided by Cholinergics, are achieved by their ability to increase acetylcholine brain level. Acetylcholine is produced by a combination of acetate and Choline that we can get from our everyday nutrition, like meat, soya and egg yolks. Though, its content in food is not enough to enhance the brain functions. First of all, it is important to know that hippocampus level of acetylcholine is essential for memory consolidation process and long-term memory.
Besides, acetylcholine improves the plasticity of neurons, as well as the rate of new connections creation in the brain. This is also really meaningful for other cognitive functions, like calculations and analyses execution, as well as attentiveness.
O enhance your brain functions with Acetylcholine, we advise you use a high-quality Choline source, which can be found in such supplements, as Alpha GPC Choline, Citicoline and Centrophenoxine. You may also find compounds that include Huperzine A or other inhibitors of acetylcholinesterase, which prevent its breakdown in the brain.
It is a well known fact that Dopamine helps us feeling better and happier. This is due to the fact that this neurochemical makes a part of the rewards system, which is responsible for the pleasant feelings we get. Usually, we get such feelings when going through some pleasant experiences in our life. However, high content of Dopamine lowers stress and depression, as well as nervousness and psychic stress.
Dopaminergics enhance Dopamine release in the pre-frontal cortex and enhance your energy and cognitive functions. You may find various nootropics from the Dopaminergic class, still the most commonly used remain L-Dopa, Sulbutiamine and L-Tyrosine.
The class of Metabolics is clearly defined already by its title. It is the group of nootropic supplements that exert their action through improving your neurons metabolism. Other kind of nootropics, included in this category, is the drugs that enhance the flow property of the neurons cell membranes (Ginkgo Biloba, Phosphatidylserine, Creatine). This promotes the cells ability to capture the required materials and nutrients.
The first subcategory differs by its vasodilators ability (Vinpocetine), which consists in the enhancement of the blood flow rate to your brain. This process allows the brain to get the important components (glucose and oxygen) for making ATP, which is the energy, required for your neurons to power all multiple processes within the cells.
Serotonin is a neurotransmitter, which controls brain processes, associated with mood, sleep and appetite. Serotonergics increase its level in the brain, thus saving people from depressed states, loss of sleep and motivation.
When exposed to sunlight, you may increase your Serotonin level. Such supplements, as L-Tryptophan and 5-HTP are commonly used Serotonergics that boost your Serotonin level to a higher degree. You may also get this effect from various nootropics that enhance the mood, since many of them also affect Serotonin brain level through acting in quality of Serotonin Reuptake Inhibitors or as the precursors to this chemical.