The Latest Catalog of Cognition Enhancing Nootropics

As you might have read earlier in our guide, the effects of the nootropic drugs result from their ability of influencing the brain to the extent that the cognitive functions are significantly enhanced, as well as relaxation and stimulation in some cases. We didn’t make up the list by any systematic order, so what you get is a fully randomized catalog, which aims at providing you with the description of almost every nootropic available.

All information contained further is given certainly for informational purposes and under no circumstance should be considered an encouragement to use any or all nootropics at once. When you make the choice on whether you shall or shall not use the nootropic drugs, you do it at own risk. Solely for your convenience, we have compiled the information about popular drugs at the present market that are capable of inducing the nootropic effect.


piracetamPiracetam influences acetylcholine brain receptors, thus requiring you to take choline together with it for avoiding obtuse headaches. Its action expresses in an inflow of fresh and clear energy, makes you more focused and mentally enduring. It is an original nootropic drug, exerting a relatively gentle effect in its standard dose. Some people prefer taking really high Piacetam dosages (4000-24000 mg) for boosting the effects of this drug.


aniracetamThe comparison of Aniracetam and Piracetam effects (focus, mood, memory) shows that the former exerts a five times higher action. In addition to that, it posseses the best anxiolytic effect amongst the smart drugs. Aniracetam is recommended for people seeking cognitive enhancement of a greater force, than you can get from Piracetam. People, really fond of nootropic drugs prefer stacking Aniracetam with such stimulants, like Adderal, Adranafil and Modanafil for softening the stimulant. Using Aniracetam before any kind of stressful events, requiring high focus and brain activity, is a great idea, but don’t forget that just like Piracetam, Aniracetam requires joint use with choline for avoiding such adverse event, like headache.


pramiracetamStanding at the highest potency level among the main cognitive enhancers, Pramiracetam (not Phenylpiracetam), is 30 times stronger than Piracetam and provides prominently higher benefits for the overall cognitive abilities. While being so strong, Pramiracetam requires joint choline use and compliance with the daily dosing regime, not exceeding 250 to 500 mg.


oxiracetamOxiracetam might be referred to as a speedy member of the racetam family. It is known as the “speedy racetam” for being fifteen times stronger than the original nootropic drug, created in the 60’s. Oxiracetam is perfect in stacks with stimulants (e.g. caffeine), yet it also requires choline for saving your head from dull ache and realizing its true effects.


tianeptineTianeptine is capable of giving you both energy boost and falling asleep easier. It depends on the substance you are stacking it with. This nootropic drug exerts a significant action on such brain receptors, as serotonin and dopamine, which allows it acting both ways.


sulbutiamineAn extremely stimulating drug, providing a variety of nootropic effects, like highly enhanced energy, productivity, focus and motivation. Sulbutiamine can surely be called one of the best cognition enhancing and stimulation drugs on the present nootropic market. Extremely high single dose of 500 to 5000 mg allows achieving the maximum boost, though it might result in an overdose. Remember that tolerance is an individual factor, so paying attention to it is really important, if you are planning on using Sulbutiamine in such dosage. Its effect is dose and tolerance dependant and lasts six to twelve hours, so it is advised to be taken in the first part of the day.


centrophenoxinA very interesting Choline form, Centrophenoxine, is a derivative of CDP Choline, capable of providing many effects, similar to the energy and focus enhancement, provided by supplementing DMAE. It is not yet known for sure, whether Centrophenoxine is stronger than CDP Choline. However, there is a prominent difference between the effects of these two drugs. Generally, people take Centrophenoxine in a dose of 100 mg.

CDP Choline

cdp-cholineBy its potency, CDP Choline is similar to centrophenoxine, but it’s a lot milder in its effect than Alpha GPC Choline (strongest choline form). Standard dose of this brain drug is 250 to 500 mg per day, however a substantially higher dose should be taken, when you use high doses of ampakine-like or racetams nootropics, like Sunifiram or Noopept.

Alpha GPC Choline

Alpha-GPC-CholineAlpha GPC Choline is unique by its ability of mildly influencing Growth Hormone. Due to this, many body-builders use it for enhancing muscle gain level, when going through heavy-weight lifting workouts. This effect results from a long-term use in conjunction with a proper high-calorie nutrition and regular exercise. Aside from this effect, Alpha GPC Choline is the most powerful choline form on the nootropic market and provides 5x stronger effect than CDP Choline.


adderallAdderall is capable of bringing you above the ground, but be sure that it will hit you strongly against it, when you decide to stop using it. This Rx drug is really famous among ADHD patients, in schools, universities and business. It fills you with extreme vigor for life and euphoria, at the same time enhancing your focus and recent memory. Adderall makes you feel like a superhero, which can do everything he needs and within the shortest possible deadline. It simply breaks the limits and obstacles, making life around you wonderful and amazing. However, you will have to constantly drink water and might find it hard to eat, when you take Adderall. Other negative attributes of Adderall appear when its action ends and when you stop taking it. Withdrawal from this drug results in fatigue, depression, hunger and anxiety.


ritalinRitalin is often compared with Adderall, but Ritalin molecule is methylphenidate, while Adderall is dextroamphetamine. So now we see that these two substances really differ from one another, even though their effects and potency are quite similar. Adderall offers a euphoria rush, but when it comes to Ritalin, you will have a sort of calmer feeling. It might even make you feel tired, regardless of whether you have ADHD or not.


GalantamineThe “lucid dreaming nootropic” is the nickname, acquired by Galantamine over the time, based on its supreme acetylcholine transmission, which allows it to considerably enhance the brightness of your dreams, as well as your ability of seeing lucid dreams and controlling events in them. Besides, it boosts the thought acuity and acts as a stimulant.

Rhodiola Rosea

Rhodiola-RoseaRhodiola Rosea has been well-known as a potent adaptogen for ages. It is one of the few cognitive boosters, contained in our guide, which was found in nature from the bottom to the top with no synthetic additives, created by men. This herbal product has a reputation for diminishing depression, eliminating fatigue, enhancing focus, and, in higher doses, for quite a significant stimulating action. Rhodiola doesn’t require you taking choline with it due to the fact that it doesn’t affect acetylcholine receptors. On the contrary, it only exerts a very mild effect on GABA, dopamine and serotonin receptors.


AshwagandhaHaving almost the same action as Rhodiola Rosea, Ashwagandha differs from it by its higher total potency. These two adaptogens are similar by their origin, both being natural herbal nootropics that enhance focus and memory, providing relaxation, as well. Ashwagandha also affects GABA, dopamine and serotonin receptors in a very mild way. The joint effect explains its high potency.


ALCARThe first advantage that many of you will find really pleasant is the price of Acetyl-L-Carnitine (you can find it for just 4.99 USD for a 30-capsule pack). However, it has other nice advantages, like, for example, minor negative events even if you take it in high doses. In fact, it resembles choline to the extent that ALCAR suits very well, if you have to promote muscle rebuilding.


ALAALA means Alpha-Lipoic Acid, and its effects on the cognitive functions are a side-product of the additional health benefits, such as sustainable improvements for both lung and heart functions.


CerebrolysinCerebrolysin is allegedly the strongest brain drug, but you will surely find it hard to find and get it. It belongs to the category of “extreme nootropics”. Even though it sounds perfect, it does have a disadvantage. You can only use it through the intramuscular injections, while the other administration methods will not result in any effect whatsoever.


PhenylpiracetamOnly Modafinil and Adderall are stronger than Phenylpiracetam, when it comes to such nootropic effects, like productivity improvement, clear thinking and cognitive enhancement. However, there is not enough information about the extent to which Phenylpiracetam boosts memory, focus or energy. It passes the blood-brain barrier in not more than 60 minutes and works on such brain receptors, as norepinephrine, dopamine, acetylcholine and dopamine. Phenypiracetam stands among the most potent nootropics, being an ADHD Rx phsychostimulant.


AdrafinilAdranafil is effective by 99% in comparison to Provigil, which is the brand drug. The legal drug Adranafil also works on inducing memory, focus and energy. You can buy this Modafinil pro-drug on most websites that sell nootropics. The advantage is that you don’t have to wait for the delivery for a long time. Adranafil will be delivered to you in just a few days, while as and will have you waiting several weeks for your original Modafinil.


modafinilModafinil is slightly stronger than Adrafinil, but the actual difference is so small that people rarely notice it, when they compare the effects of Modafinil 200 mg to Adrafinil 600 mg. and offers you a 21-day delivery period for Modafinil (though you can choose an express 7-days delivery on So you see that you can easily find and buy this schedule IV Rx drug on the online stores.


DesmopressinDesmopressin is defined by biohackers as the “photographic memory drug”. However, it is really dangerous and not advised for use. While you can still buy it on, you should be aware of the fact that it doesn’t offer you actual photographic memory, although the short-time memory will surely be significantly improved.


L-TheanineL-Theanine works by exasperating GABA brain receptors, thus leading to relaxation. However, people frequently use it in stacks with caffeine to gain a high stimulating effect. The action it exerts is comparable to the one you can get from melatonin supplements. Clinical investigations on mice have proven that L-Theanine boosts memory, advances the rapid eye movement sleep, improves anxiety symptoms and reduces depression.


PhenibutOne of the nootropics that advance relaxation and help reduce nervousness is Phenibut, the action of which might remind you of serving a small alcoholic drink. People take it for getting an incitement, as well as for stimulation and creativity boost.


PicamilonThe action of Phenibut is a bit milder than the one of Picamilon, though they are quite alike. You may add choline, when you use Picamilon, which might enhance its effects (relaxation, lower anxiety). However, choline is not mandatory, since Picamilon mainly works on GABA neurotransmitter.


NoopeptNoopept is another nootropic product that requires plenty choline, when you use it. Though it doesn’t belong to racetams family, its effect was compared to Piracetam during the investigations, which have proven its 1000 times higher potency. To cut the long story short, Noopept 10 mg offers stronger effect than Piracetam 1 g.


SunifiramSunifiram is another brain drug that requires joint use of choline. Even though this medicine originates from the molecule that Piracetam also originates from, its potency is considerably higher than even of the strong Noopept.  Sunifiram belongs to the Ampakine nootropics group, and due to the fact that it strongly interacts with glutamatergic AMPA receptor, its effect, on a per-mg basis, is 5000x stronger than Piracetam.


ColuracetamColuracetam is quite a costly nootropic, the use of which doesn’t imply Choline administration for its effects potentiating. However, it is yet untested and considerably a newcomer, still, compared to Piracetam, it is one thousand times more potent than the latter.


NefiracetamNefiracetam is capable on promoting strong euphoria in higher doses, but is quite hard to be found. If it happens so that you manage to get your hands on Nefiracetam, you should be aware of the fact that, just like Coluracetam, it is new and still untested, though quite a costly nootropic of racetams family. By its effects, it is alike to Sunifiram and Noopept, and by its potency, it is five hundred times stronger than Piracetam on a per-mg basis.


FasoracetamIf you decide to turn your path towards using Fasoracetam, you have to prepare for a very long search, since it is quite rare to be found. In fact, you should be very careful with it, if you do manage to find it, because there is a high probability of finding a fake version. However, the 100% pure version would offer you the effects of Phenylpiracetam and Adrafinil put together, and would require you taking a serious amount of choline to avoid headaches.


UnifiramUnifiram is a very close relative of the nootropic product Sunifiram, but it is a lot more costly and more difficult to be synthesized. These are the reasons you will hardly be able to find or buy this Ampakine variant of Sunifiram, though they are identical in effects.

Dimethylaminoethanol (DMAE)

DimethylaminoethanolDimethylaminoethanol may serve you perfectly in enhancing the effects of racetam nootropics. Its standard doses will boost your memory and thought clearness, but its long-term use has a variety of effects to offer. Very often, people use DMAE on a long-term basis to fix skin complexion problems, like aging and loss of skin vitality, but due to its nootropic properties, long use of DMAE may also exert choline-like effects.


ArmodafinilArmodafinil offers a prolonged effect that lasts 15 to 20 hours, so you’d better take it, if there are a lot of working hours to follow. The pharmaceutical form of Armodafinil is tablets of 150 mg. It passes the blood brain barrier a lot more rapidly than Modafinil, which results in milder adverse events  and higher effectiveness in comparison with Provigil.

5-Hydroxytrptophan (5-HTP)

5-HTP5-HTP is a precursor of amino acid in tryptophan that actively assists in serotonin brain production. People may take 5-Hydroxytrptophan for reaching two opposite goals: whether getting a strong sleep aid, or for smoothing caffeine high.


PhenylalanineBeing the precursor to dopamine, Phenylalanine stands as the 1st aminoacid in the dopamine creation process, which goes the following way: Phenylalanine→L-Tyrosine→L-Dopa→Dopamine. Higher doses of Phenylalanine bring one long-lasting and stimulating clarity flash.


L-DopaDoctors prescribe L-Dopa to patients with Parkinson’s disease low on dopamine for a good reason. It is created immediately before dopamine enters the neurotransmitter cycle of the brain.


CreatineAside from being used by bodybuilders as an effective supplement in their workouts, Creatine proved to be a great helper in improving the Adenosine Triphosphate brain levels, which attributes to shortening of body and mind recovery period, as well as promotes higher metal endurance and energy level. Prolonged use of Creatine helps preventing the Alzheimer’s disease. Even after you stop taking Creatine, it is still capable of reducing tiredness and producing satellite cells in the muscles at a more rapid pace.

Huperzine A

Huperzine-AThe active ingredient of the herbal brain boosting drug Huperzine A is Huperzine Serrata, which can be found in many nootropic stacks, as well as in stop smoking aids for its ability of reducing the cravings. Huperzine A works on gamma-Aminobutyric and serotonin receptors, and enhances relaxation and thought clarity. It is quite similar to another potent herbal drug Vinpocetine, which also exerts nootropic effects.


VinpocetineVinpocetine was stacked by Alpha Brain along with Huperzine A for creating a strong and purely natural stack. The reason for this is the ability of Vinpocetine to increase the potency of other drugs and nootropics. Even though the effects of Vinpocetine are quite mild, they resemble the effects of Choline, so by stacking Vinpocetine with any cholinergic nootropic you will considerably enhance its effects.


MarijuanaMarijuana is not something you would consider to be a nootropic at the first sight. Besides, it might cause a variety of withdrawal symptoms, like depressed mood, restlessness, changes in sleeping and eating, and unfocused mind. On the other hand, multiple investigations have proven that Marijuana improves he rapid eye movement sleep, boosts energy, reduces nervousness, and provides euhoria. Due to its ability of lowering cortisol level, Marijuana can be taken as an anxiolitic or a sleep aid.


NicotineNicotine is a very addictive substance, causing severe withdrawal symptoms, when you quit using it. Despite this, many people note the euphoric feeling that nicotine gives them for a short period of time after administration. In fact, this active chemical of tobacco is among the best cognition boosters on our list for its stimulating and anxiety eliminating properties. Don’t forget about the negative effects and think a lot before you start using it.


CaffeineIn high doses, Caffeine may promote euphoria, while as standard doses might help you avoid sleepiness and fatigue. Caffeine is well-known for its strong nootropic effects centuries in a row. There is even a saying that the British kingdom has grown on tea.


KratomKratom (Mitragyna speciosa) behaves as a μ-opiod receptor agonist (resembles the effects of poppy, but to a noticeably lesser extent) and promotes euphoria. Depending on the dose and form taken, it can offer you either stimulating, or sedating effect. Kratom is an addictive product and is capable of producing withdrawal symptoms, if you mess up with the dosing. Even though these symptoms are comparable to opioid withdrawal symptoms, they are considerably milder.

If you are still not sure, whether the nootropics will work for you or now, here’s something for you to consider.

Each individual is certainly unique, and his reaction, as well as response to any kind of drug, might differ really much from his friend’s body response. You should understand that no one can predict the effects that a brain booster exerts namely on your organism, though you should never forget to keep to the recommended dosages and regime. As we have suggested, experimenting with different nootropics might help you find your perfect one, but be sure that the online provider of nootropic drugs is a reliable one.

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